Key result
Methadone use is associated with potentially fatal Q-T interval prolongation and torsades de pointes, necessitating thorough patient history and baseline ECG monitoring.
Why the study?
Does methadone use increase the risk of Q-T interval prolongation and torsades de pointes?
Population
Patients treated with methadone, including illicit opioid users
Design
Review
Authors
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Supports QT monitoring for methadone users; leaves open optimal prevention strategies.
Does methadone use increase the risk of Q-T interval prolongation and torsades de pointes?
Methadone use carries a risk of potentially fatal Q-T interval prolongation and torsades de pointes, highlighting the need for baseline ECG monitoring and risk factor assessment.
Stringer et al. (2009) conducted a review in Opioid addiction / Methadone users. Methadone was evaluated on Q-T interval prolongation and torsades de pointes. Methadone use is associated with potentially fatal Q-T interval prolongation and torsades de pointes, necessitating thorough patient history and baseline ECG monitoring.
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