Key result
High platelet distribution width in patients with acute coronary syndrome was significantly associated with higher GRACE scores (139 vs. 126) and lower TIMI flow grades.
Why the study?
Platelets play a pivotal role in ACS pathogenesis, and this study investigated whether platelet distribution width is associated with ACS severity, angiographic intracoronary thrombus burden, and TIMI flow grade.
Does platelet distribution width correlate with acute coronary syndrome severity and coronary thrombus burden in patients with ACS?
Observational (n=149)
No
Does platelet distribution width correlate with acute coronary syndrome severity and coronary thrombus burden in patients with ACS?
Absolute Event Rate: 139% vs 126%
p-value: p=<0.05
Platelet distribution width correlates with GRACE scores in patients with acute coronary syndrome, suggesting it may serve as a marker for disease severity.
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Hızır Okuyan (2023) conducted an observational in Acute Coronary Syndrome (n=149). High platelet distribution width (PDW) vs. Low platelet distribution width was evaluated on GRACE score (p=<0.05). High platelet distribution width in patients with acute coronary syndrome was significantly associated with higher GRACE scores (139 vs. 126) and lower TIMI flow grades.
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