Why the study?
Are ACE I/D and ACTN3 R/X polymorphisms associated with functional muscle properties in Lithuanian elite athletes?
Population
193 Lithuanian elite athletes and 250 controls from the general Lithuanian population
Comparison
ACE I/D and ACTN3 R/X polymorphisms vs ACE D/D and ACTN3 R/R genotypes
Design
Case-control
Key result
ACE I/I and I/D genotypes were more frequent in Lithuanian elite athletes than controls, and athletes with ACE I/I and ACTN3 X/X genotypes demonstrated better grip strength and vertical jump.
Authors
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May inform power-sport selection in Lithuanian athletes; leaves open replication in larger, diverse cohorts before any clinical use.
Case-Control (n=443)
Are ACE I/D and ACTN3 R/X polymorphisms associated with functional muscle properties in Lithuanian elite athletes?
The ACE I and ACTN3 X alleles are associated with better speed and power performance in Lithuanian elite athletes, suggesting potential utility in sport type selection.
Ginevičienė et al. (2011) conducted a case-control in Physical performance (n=443). ACE I/D and ACTN3 R/X polymorphisms vs. General population / ACE D/D and ACTN3 R/R genotypes was evaluated on Genotype frequencies and muscle strength (grip strength and vertical jump). ACE I/I and I/D genotypes were more frequent in Lithuanian elite athletes than controls, and athletes with ACE I/I and ACTN3 X/X genotypes demonstrated better grip strength and vertical jump.