Key result
Laparoscopic colorectal resection in high-risk patients (ASA 4) had a 26% postoperative complication rate, not significantly different from no-risk (12%) or low-risk (18%) patients (p>0.05).
Why the study?
Is laparoscopic colorectal resection safe for high-risk patients with severe comorbidities?
Cohort (n=557)
No
Is laparoscopic colorectal resection safe for high-risk patients with severe comorbidities?
Absolute Event Rate: 26% vs 12%
p-value: p=>0.05
Laparoscopic colorectal resection can be performed safely in high-risk patients with severe comorbidities without significantly increasing overall complications or postoperative hospital stay.
May support laparoscopic colorectal resection in high-risk patients; leaves open randomized confirmation.
BACKGROUND/AIMS: This study assessed the short term results of laparoscopic colorectal resection for high risk patients. METHODOLOGY: Five hundred and fifty seven consecutive patients underwent an elective laparoscopic colorectal cancer resection by the same surgical team between April 2007 and December 2010. No risk patients in ASA class 1 (Group N, n=222), low risk patients with the systemic disease under the control in ASA class 2 and 3 (Group L, n=320), high risk patients with severe comorbidities in ASA class 4 (Group H, n=15) were respectively compared. RESULTS: The median blood loss count was significantly higher than the other group (N: 26 g, L: 22 g) in group H (59 g; p<0.05). On the other hands, the less lymphadenectomy was performed and a reconstruction with anastomosis was denied in group H. The incidence of postoperative complications was not significantly different in each group (N: 12%, L: 18%, H: 26%; p>0.05). There was the significant difference of the incidence with systemic complication (respiratory failure, ascites and delirium) in group H. The median postoperative hospital stay was not significantly different in each group (POD7; p>0.05). Hospitalization death occurred in three patients (0.5%) by uncontrollability of the systemic disease, two patients in group L and one patient in group H. CONCLUSIONS: Laparoscopic colorectal resection for high risk patients was performed safely without increasing complications and postoperative hospital stay.
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Tashiro et al. (2012) conducted a cohort in Colorectal cancer (n=557). Severe comorbidities (ASA class 4) vs. No risk (ASA class 1) and low risk (ASA class 2-3) was evaluated on Postoperative complications (p=>0.05). Laparoscopic colorectal resection in high-risk patients (ASA 4) had a 26% postoperative complication rate, not significantly different from no-risk (12%) or low-risk (18%) patients (p>0.05).
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