What is the clinical evidence from this study?

Population: Healthy (n=6). Intervention: Near-infrared spectroscopy (NIRS) vs. Direct femoral vein sampling. Primary outcome: Changes in hemoglobin and/or myoglobin O2 saturation during exercise.

February 1, 1999Journal of Applied Physiology

Comparison of femoral blood gases and muscle near-infrared spectroscopy at exercise onset in humans

View Full Paper

Ask AI

Bookmark

Key result

Near-infrared spectroscopy (NIRS) does not provide a reliable estimate of hemoglobin and/or O2 saturation as reflected by direct femoral vein sampling during moderate-intensity exercise.

Why the study?

Does near-infrared spectroscopy (NIRS) reliably estimate hemoglobin/myoglobin O2 saturation compared to direct femoral vein sampling during exercise in healthy subjects?

Structured PICO

Does near-infrared spectroscopy (NIRS) reliably estimate hemoglobin/myoglobin O2 saturation compared to direct femoral vein sampling during exercise in healthy subjects?

Population

6 healthy subjects who performed transitions from rest to moderate-intensity two-legged kicking exercise under varying inspired O2 conditions.

Exposure

Near-infrared spectroscopy (NIRS) measurement of hemoglobin/myoglobin O2 saturation (IR-SO2) over the vastus lateralis muscle during transitions from rest to 48 +/- 3 W two-legged kicking exercise while breathing 14, 21, or 70% inspired O2

Comparator

Direct femoral venous O2 saturation (SfvO2) measured via blood samples drawn simultaneously

Outcome

Agreement between IR-SO2 and SfvO2 changes at the onset and during 5 minutes of exercisesurrogate

Near-infrared spectroscopy does not reliably estimate muscle oxygen saturation compared to direct venous sampling during exercise.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

NIRS may track muscle O2 saturation changes during exercise; leaves open its validity as a noninvasive venous surrogate.

Cite This Study

MacDonald et al. (1999) studied Healthy (n=6). Near-infrared spectroscopy (NIRS) vs. Direct femoral vein sampling was evaluated on Changes in hemoglobin and/or myoglobin O2 saturation during exercise. Near-infrared spectroscopy (NIRS) does not provide a reliable estimate of hemoglobin and/or O2 saturation as reflected by direct femoral vein sampling during moderate-intensity exercise.

synapsesocial.com/papers/6a6bc053c681b07c2424a246 https://doi.org/10.1152/jappl.1999.86.2.687

View Full Paper

Ask AI

Bookmark

Comparison of femoral blood gases and muscle near-infrared spectroscopy at exercise onset in humans

Structured PICO

Discussion

Implication

Cite This Study

Comparison of femoral blood gases and muscle near-infrared spectroscopy at exercise onset in humans

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider