Key result
Transcatheter pulmonary valve replacement was associated with a lower risk of short-term ventricular arrhythmias compared to surgical replacement (adjusted HR 0.20, p=0.002).
Why the study?
Does transcatheter pulmonary valve replacement reduce ventricular arrhythmia burden compared to surgical pulmonary valve replacement in patients with repaired congenital heart disease?
Cohort (n=302)
No
Does transcatheter pulmonary valve replacement reduce ventricular arrhythmia burden compared to surgical pulmonary valve replacement in patients with repaired congenital heart disease?
Hazard Ratio: 0.2
p-value: p=0.002
Transcatheter pulmonary valve replacement is associated with a significantly lower short-term risk of ventricular arrhythmias compared to surgical replacement, though mid- and late-term risks are comparable.
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TC-PVR was associated with lower short-term VA burden than S-PVR; leaves open long-term outcome differences in CHD.
Wadia et al. (2018) conducted a cohort in Congenital heart disease (n=302). Transcatheter pulmonary valve replacement (TC-PVR) vs. Surgical pulmonary valve replacement (S-PVR) was evaluated on Composite of non-intraoperative ventricular arrhythmia (symptomatic/recurrent non-sustained VT requiring therapy, sustained VT or ventricular fibrillation) at 0-1 month (HR 0.20, p=0.002). Transcatheter pulmonary valve replacement was associated with a lower risk of short-term ventricular arrhythmias compared to surgical replacement (adjusted HR 0.20, p=0.002).
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