Key result
Dynamic echocardiographic changes, such as baseline RA area ≥27 cm2 (HR 2.41; 95% CI 1.21-4.80), were significantly associated with 1-year all-cause mortality in CHF patients with functional TR.
Why the study?
Do dynamic right ventricular morphologic and functional changes on serial echocardiography predict 1-year all-cause mortality in patients with chronic heart failure and significant functional tricuspid regurgitation?
Population
101 consecutive patients with chronic heart failure and moderate or severe functional tricuspid…
Design
Cohort
Follow-up
median 305 days after the last echocardiography
Authors
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RV dysfunction assessment may aid risk stratification in CHF with functional TR; leaves open whether targeted RV therapies improve survival.
Cohort (n=101)
Do dynamic right ventricular morphologic and functional changes on serial echocardiography predict 1-year all-cause mortality in patients with chronic heart failure and significant functional tricuspid regurgitation?
Hazard Ratio: 2.41 (95% CI 1.21–4.8)
p-value: p=0.013
Dynamic right ventricular morphological and functional changes on serial echocardiography, including paradoxical sPAP reduction and progressive RV/RA enlargement, strongly predict 1-year mortality in CHF patients with significant functional TR.
Hu et al. (2016) conducted a cohort in Chronic heart failure with significant functional tricuspid regurgitation (n=101). Dynamic echocardiographic changes (e.g., baseline RA area ≥27 cm2) vs. Absence of these echocardiographic changes was evaluated on All-cause mortality (HR 2.41, 95% CI 1.21-4.80, p=0.013). Dynamic echocardiographic changes, such as baseline RA area ≥27 cm2 (HR 2.41; 95% CI 1.21-4.80), were significantly associated with 1-year all-cause mortality in CHF patients with functional TR.
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