Key result
Short-term residence at high altitude increased mean arterial blood pressure (102 vs 91 mmHg, P<0.05) and reduced vasodilatory responses to adenosine and ATP.
Why the study?
Does chronic hypoxia alter arterial blood pressure and vasodilatory responses to adenosine and ATP in healthy men?
Observational (n=10)
Does chronic hypoxia alter arterial blood pressure and vasodilatory responses to adenosine and ATP in healthy men?
Absolute Event Rate: 102% vs 91%
p-value: p=< 0.05
Short-term residence at high altitude increases arterial blood pressure and blunts vasodilatory responses to adenosine and ATP in healthy men.
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May inform altitude exposure monitoring in healthy adults; leaves open translation to patients or therapeutic targeting.
Calbet et al. (2014) conducted an observational in Healthy (n=10). Chronic hypoxia (high altitude residence) vs. Sea level was evaluated on Mean arterial blood pressure (p=< 0.05). Short-term residence at high altitude increased mean arterial blood pressure (102 vs 91 mmHg, P<0.05) and reduced vasodilatory responses to adenosine and ATP.
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