Key result
18F-FDG PET/CT SUVmax was significantly higher in malignant pulmonary artery lesions compared to pulmonary thromboembolism (10.2 vs 1.7; P<0.001), with no overlap between groups.
Why the study?
Does (18) F-FDG PET/CT differentiate malignant from benign pulmonary artery lesions in patients with suspicious filling defects on CT?
Population
18 subjects with 26 low-attenuated filling defects suspicious for pulmonary artery malignancy on…
Design
Cohort
Authors
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FDG-PET/CT may aid differentiation of PA lesions; leaves open need for prospective validation before clinical adoption.
Observational (n=18)
Does (18) F-FDG PET/CT differentiate malignant from benign pulmonary artery lesions in patients with suspicious filling defects on CT?
Absolute Event Rate: 10.2% vs 1.7%
p-value: p=<0.001
(18) F-FDG PET/CT is a highly useful imaging modality for differentiating malignant from benign pulmonary artery lesions in patients with inconclusive low-attenuation filling defects on contrast-enhanced chest CT.
Lee et al. (2012) conducted an observational in Pulmonary artery lesions mimicking pulmonary embolism (n=18). 18F-FDG PET/CT vs. Pulmonary thromboembolism (benign lesions) was evaluated on Maximum standardized uptake value (SUVmax) (p=<0.001). 18F-FDG PET/CT SUVmax was significantly higher in malignant pulmonary artery lesions compared to pulmonary thromboembolism (10.2 vs 1.7; P<0.001), with no overlap between groups.
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