December 2, 1995European Heart Journal
Molecular genetics of dilated cardiomyopathies
Key result
Familial idiopathic dilated cardiomyopathy is a genetically heterogeneous condition, with X-linked forms linked to the dystrophin gene and right ventricular dysplasia localized to chromosome 14.
Population
Patients with idiopathic dilated cardiomyopathy (IDC) and familial right ventricular cardiomyopathy
Design
Review
Authors
Discussion
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Implication
May support family screening in IDC; leaves open specific gene identification for targeted therapies.
Structured PICO
P
Population
Patients with idiopathic dilated cardiomyopathy (IDC) and familial right ventricular cardiomyopathy
This review highlights the significant role of genetic factors and heterogeneity in the pathogenesis of idiopathic dilated cardiomyopathy and related conditions.
Cite This Study
Mestroni et al. (1995) conducted a review in Idiopathic dilated cardiomyopathy (IDC). Genetic factors was evaluated. Familial idiopathic dilated cardiomyopathy is a genetically heterogeneous condition, with X-linked forms linked to the dystrophin gene and right ventricular dysplasia localized to chromosome 14.