Key result
Ergonovine maleate provoked near-total occlusion of a major coronary vessel in 75% (3 of 4) of patients with Prinzmetal angina, compared to 0% (0 of 10) of patients without the condition.
Why the study?
Does provocative pharmacoangiography with ergonovine maleate induce coronary arterial spasm in patients with Prinzmetal variant angina?
Population
21 consecutive patients with Prinzmetal angina (PMA) and 10 patients without PMA.
Comparison
Provocative pharmacoangiography with ergonovine… vs Patients without Prinzmetal angina receiving the…
Design
Cohort
Authors
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Ergonovine provocation may aid Prinzmetal angina diagnosis; leaves open validation in larger prospective studies.
Observational (n=31)
Does provocative pharmacoangiography with ergonovine maleate induce coronary arterial spasm in patients with Prinzmetal variant angina?
Absolute Event Rate: 75% vs 0%
Provocative pharmacoangiography with ergonovine maleate successfully identifies coronary artery spasm as the mechanism of ischemia in patients with Prinzmetal variant angina.
Higgins et al. (1976) conducted an observational in Prinzmetal angina (n=31). Ergonovine maleate vs. Patients without Prinzmetal angina was evaluated on Provocation of coronary arterial spasm (near-total occlusion of a major vessel). Ergonovine maleate provoked near-total occlusion of a major coronary vessel in 75% (3 of 4) of patients with Prinzmetal angina, compared to 0% (0 of 10) of patients without the condition.
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