Key result
A subset of baroreceptor fibers in rabbits is spontaneously active at very low intrasinus pressures and responds to chemical stimuli like 5-hydroxytryptamine, nicotine, and hypercapnia.
Population
Urethane-anesthetized spontaneously breathing rabbits
Comparison
Alterations in carotid sinus pressure and… vs Baseline conditions or different intrasinus…
Design
Preclinical
Authors
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Hypothesis-generating for chemosensitive low-pressure baroreceptors; leaves open relevance to human baroreflex physiology.
Identifies a subset of baroreceptor fibers in rabbits that are spontaneously active at very low pressures and sensitive to chemical changes.
Qu et al. (1991) studied this question. Intrasinus pressure changes and chemical stimuli was evaluated on Firing rate of baroreceptor and chemoreceptor fibers. A subset of baroreceptor fibers in rabbits is spontaneously active at very low intrasinus pressures and responds to chemical stimuli like 5-hydroxytryptamine, nicotine, and hypercapnia.
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