Key result
Large increases in aortic arch pressure resulted in an average 11% decrease in the pressure gradient between the perfused vein and the femoral vein in the dog hind limb.
Population
Dogs (perfused hind limb model with vascularly isolated aortic arch and carotid sinuses)
Comparison
Increases in aortic arch pressure, carotid sinus… vs Baseline/control state
Design
Preclinical
Authors
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Suggests baroreflex control of canine hind-limb veins; leaves open translation to human physiology.
The study demonstrates that large superficial veins of the dog's hind limb participate in baroreceptor reflexes, though the nerve activities supplying arterioles and veins differ.
Hainsworth et al. (1975) studied this question. Increases in aortic arch pressure vs. Baseline pressure was evaluated on Pressure gradient between the perfused vein and the femoral vein. Large increases in aortic arch pressure resulted in an average 11% decrease in the pressure gradient between the perfused vein and the femoral vein in the dog hind limb.
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