Key result
Intermittent static quadriceps exercise significantly increased interstitial K+ and phosphate, suggesting these metabolites may contribute to the stimulation of the exercise pressor reflex.
Why the study?
Does intermittent static quadriceps exercise alter interstitial pH, K+, lactate, and phosphate in relation to MSNA, heart rate, and blood pressure in humans?
Does intermittent static quadriceps exercise alter interstitial pH, K+, lactate, and phosphate in relation to MSNA, heart rate, and blood pressure in humans?
Interstitial K+ and phosphate, but not lactate and H+, may contribute to the stimulation of the exercise pressor reflex during intermittent static quadriceps exercise.
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Should not yet alter exercise guidance; hypothesis-generating for metabolite roles in sympathetic activation.
MacLean et al. (2000) studied this question. Intermittent static quadriceps exercise vs. Rest was evaluated on Interstitial concentrations of putative stimulators of the exercise pressor reflex (lactate, phosphate, K+, H+). Intermittent static quadriceps exercise significantly increased interstitial K+ and phosphate, suggesting these metabolites may contribute to the stimulation of the exercise pressor reflex.
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