Population
Decerebrate cat model
Comparison
3- and 5-Hz hindlimb twitch contractions vs Baseline/rest
Design
Preclinical
Follow-up
10 min of recovery
Authors
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May inform mechanisms of thin-fiber afferent activation during contraction in animals; leaves open translation to human exercise pressor responses.
Simultaneous measurement of skeletal muscle interstitial metabolites and pressor responses suggests that interstitial K+ and phosphate may contribute to the stimulation of thin fiber muscle afferents during contraction.
MacLean et al. (1998) studied this question.
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