Key result
Aortic balloon valvuloplasty in newborns with critical or severe aortic stenosis required re-intervention in 20% of patients, with mortality risks associated with ventricular dysfunction.
Why the study?
Critical or severe aortic stenosis in newborns requires rapid intervention, and this study was conducted to explore a single centre's experiences with aortic balloon valvuloplasty.
What are the clinical outcomes and risk factors for re-intervention and mortality following aortic balloon valvuloplasty in newborns with critical or severe aortic stenosis?
Observational (n=52)
No
What are the clinical outcomes and risk factors for re-intervention and mortality following aortic balloon valvuloplasty in newborns with critical or severe aortic stenosis?
Aortic balloon valvuloplasty is an effective intervention for newborns with critical aortic stenosis, though re-intervention is needed in about 20% of cases and mortality is primarily driven by baseline disease severity.
Introduction: Critical or severe aortic stenosis in new-borns is a condition that requires rapid intervention. Aortic balloon valvuloplasty (ABV) is a method of choice that has been successfully performed since 1983. Aims: This study was conducted to explore the experiences of our centre. Study Design: The data of ABV performed on new-borns (n = 52) between 2007 and 2020 were retrospectively analysed to evaluate follow-up of the cases. Materials and Methods: Patients were divided into 4 groups according to procedural immediate results. Results: Left ventricular endocardial fibroelastosis and left ventricular systolic dysfunction were detected in 18 (34.6%) and 19 (36.5%) patients, respectively and there was a significant association between fibroelastosis and left ventricular dysfunction (P < 0.05). The preprocedural echocardiographic mean gradient was significantly lower in the unsuccessful group (P < 0.41). The mean hospital stay day was shorter in the group with optimal results without statistical significance (P = 0.055). Immediate inadequate results after the procedure were detected as a major risk for re-intervention. Re-intervention was required in one-fifth of the patients and the most common cause was aortic stenosis. The risk factors of mortality were found to be associated with the disease itself such as ventricular dysfunction, being critical aortic stenosis instead of procedural reasons. Conclusion: ABV is an effective method and as left ventricular dysfunction and critical aortic stenosis are risk factors of mortality, preprocedural evaluation, and quick intervention are essential.
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Beyazal et al. (2022) conducted an observational in Critical or severe aortic stenosis (n=52). Aortic balloon valvuloplasty was evaluated. Aortic balloon valvuloplasty in newborns with critical or severe aortic stenosis required re-intervention in 20% of patients, with mortality risks associated with ventricular dysfunction.
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