Key result
Percutaneous balloon aortic valvuloplasty significantly reduced the mean Doppler-derived peak gradient across the aortic valve from 75.1 to 32.2 (P<0.001) in newborns with critical aortic stenosis.
Why the study?
Does percutaneous balloon aortic valvuloplasty improve aortic valve gradients and postpone open heart surgery in newborns and young infants with critical congenital aortic stenosis?
Population
31 consecutive newborns and young infants with critical congenital aortic stenosis, mean age 22 days, mean…
Design
Cohort
Follow-up
mean 81 months (range 5 days-196 months)
Authors
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BAVP may postpone surgery in neonates with AS; leaves open need for prospective trials before changing practice.
Observational (n=31)
No
Does percutaneous balloon aortic valvuloplasty improve aortic valve gradients and postpone open heart surgery in newborns and young infants with critical congenital aortic stenosis?
Absolute Event Rate: 32.2% vs 75.1%
p-value: p=< 0.001
Percutaneous balloon aortic valvuloplasty is safe and effective for relieving critical congenital aortic stenosis in newborns, significantly reducing valve gradients and postponing the need for open-heart surgery.
Rossi et al. (2011) conducted an observational in Congenital aortic stenosis (n=31). Percutaneous balloon aortic valvuloplasty (BAVP) was evaluated on Mean Doppler-derived peak gradient across the aortic valve immediately after the procedure (p=< 0.001). Percutaneous balloon aortic valvuloplasty significantly reduced the mean Doppler-derived peak gradient across the aortic valve from 75.1 to 32.2 (P<0.001) in newborns with critical aortic stenosis.
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