Key result
Frailty is associated with worse outcomes, including higher risks of disability and mortality, in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement.
Why the study?
Does frailty impact mortality and morbidity in patients with severe aortic stenosis undergoing TAVR?
Does frailty impact mortality and morbidity in patients with severe aortic stenosis undergoing TAVR?
Answers are grounded in this paper and cite their sources.
Incorporating standardized frailty assessments into pre-operative risk evaluations for TAVR can improve shared decision-making and predict morbidity and mortality.
Frailty is a notably common problem in patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve replacement (TAVR) evaluation. Studies have demonstrated significant associations between frailty and worse outcomes in patients undergoing TAVR including higher risks of disability and mortality and admissions to long-term care facility. While there are multiple methods to identify and measure frailty, there is a critical need for a precise definition of frailty and its standardized assessment protocol based on well-established tests covering all aspects of the frailty, as a syndrome. Incorporation of the available frailty evaluation into pre-operative risk assessments chances of morbidity or mortality following surgery can help enhancing performance and improve shared decision-making between physicians and their patients. In this review, we present the perspectives of the impact of frailty on mortality in patients undergoing TAVR.
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Thongprayoon et al. (2017) conducted a review in Severe aortic stenosis undergoing transcatheter aortic valve replacement (TAVR). Frailty was evaluated on Mortality and disability. Frailty is associated with worse outcomes, including higher risks of disability and mortality, in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement.
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