Key result
Food supplementation with 1000 mg/day of olive leaf extract EFLA943 significantly reduced systolic blood pressure (mean difference ≤13 mmHg vs 500 mg/day) in borderline hypertensive twins.
Why the study?
Does olive leaf extract EFLA943 reduce blood pressure in borderline hypertensive monozygotic twins?
Population
40 borderline hypertensive monozygotic twins
Comparison
Olive leaf extract EFLA943 500 mg/day or 1000… vs Advice on a favourable lifestyle or lower dose
Design
Other, Open study (open-label)
Follow-up
8 weeks
Authors
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Olive leaf extract may modestly aid mild hypertension; leaves open efficacy as non-drug option pending RCTs.
RCT (n=40)
Open-label
Does olive leaf extract EFLA943 reduce blood pressure in borderline hypertensive monozygotic twins?
Effect estimate: mean systolic difference ≤13 mmHg (1000 vs 500 mg)
High-dose olive leaf extract (1000 mg/day) significantly reduces blood pressure and LDL-cholesterol in borderline hypertensive individuals.
Perrinjaquet-Moccetti et al. (2008) conducted an RCT in Borderline hypertension (n=40). Olive leaf extract EFLA943 vs. Advice on a favourable lifestyle was evaluated on Blood pressure (mean systolic difference ≤13 mmHg (1000 vs 500 mg)). Food supplementation with 1000 mg/day of olive leaf extract EFLA943 significantly reduced systolic blood pressure (mean difference ≤13 mmHg vs 500 mg/day) in borderline hypertensive twins.
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