Key result
A 60-year-old woman with significant emotional distress developed a rare mid-ventricular variant of Takotsubo cardiomyopathy, which completely resolved with preserved ejection fraction at one month.
Why the study?
Different variants of Takotsubo cardiomyopathy have been described recently, but atypical patterns of left ventricle dysfunction may be underrecognized.
Case Report (n=1)
This case highlights the importance of recognizing the mid-ventricular variant of Takotsubo cardiomyopathy, an atypical pattern of left ventricular dysfunction that may be underrecognized.
Mid-ventricular TC variant recognition may refine acute diagnosis; leaves open prospective data on triggers, recurrence, and outcomes.
Different variants of Takotsubo cardiomyopathy (TC) have been described recently. In the present case, we report a post-menopausal woman who had been experiencing significant emotional distress, admitted with typical chest pain, electrocardiographic changes, and elevated troponin levels. She underwent left heart catheterization that demonstrated mild non-obstructive coronary disease and mid-ventricular focal wall motion abnormality, consistent with the mid-ventricular variant of TC. One month after her discharge, a repeated echocardiogram showed preserved ejection fraction and no wall motion abnormalities. In the mid-ventricular variant, we usually observe a unique end-systolic appearance that resembles a Greek vase. It is possible that atypical patterns of left ventricle (LV) dysfunction related to TC are being underrecognized. Therefore, this case study highlights the importance of recognizing less frequent variants of TC.
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Lima et al. (2020) conducted a case report in Takotsubo cardiomyopathy (mid-ventricular variant) (n=1). Emotional distress was evaluated on Left ventricular function recovery. A 60-year-old woman with significant emotional distress developed a rare mid-ventricular variant of Takotsubo cardiomyopathy, which completely resolved with preserved ejection fraction at one month.
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