Key result
Resveratrol 10 mg daily for 3 months significantly improved left ventricular diastolic function (p<0.01), endothelial function (p<0.05), and lowered LDL levels (p<0.05) in post-infarction patients.
Why the study?
Does resveratrol improve left ventricular function, endothelial function, and hemorheological parameters in patients with stable coronary artery disease after myocardial infarction?
Population
n=40 Caucasian patients with stable coronary artery disease after myocardial infarction
Comparison
Resveratrol 10 mg oral capsule once daily for 3… vs Placebo
Design
RCT, Randomized into two groups, Double-blind, placebo controlled
Follow-up
3 months
Authors
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Small RCT suggests post-MI LV benefits; leaves open clinical adoption pending larger trials.
RCT (n=40)
Double-blind
randomized
Does resveratrol improve left ventricular function, endothelial function, and hemorheological parameters in patients with stable coronary artery disease after myocardial infarction?
p-value: p=<0.01
Resveratrol supplementation at 10 mg daily for 3 months improves surrogate markers of cardiovascular health, including diastolic function, endothelial function, and LDL cholesterol, in post-myocardial infarction patients.
Magyar et al. (2012) conducted an RCT in stable coronary artery disease (n=40). Resveratrol vs. Placebo was evaluated on Left ventricular function, flow-mediated vasodilation, laboratory and hemorheological parameters (p=<0.01). Resveratrol 10 mg daily for 3 months significantly improved left ventricular diastolic function (p<0.01), endothelial function (p<0.05), and lowered LDL levels (p<0.05) in post-infarction patients.
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