Key result
Refeeding underfed adult cows increased GLUT4 protein content in perirenal adipose tissue by 250% and increased lipoprotein lipase activity across adipose and muscle tissues.
Why the study?
Does nutritional status (underfeeding and refeeding) alter GLUT4 protein content and lipoprotein lipase activity in adipose tissues and muscles in adult cattle?
Population
Adult non-lactating non-pregnant Holstein cows (n=13)
Comparison
Underfeeding and refeeding vs Control diet
Design
Preclinical, Allotted to one of three groups
Follow-up
7 days underfeeding, 21 days refeeding
Authors
Loading...
Should not change human practice; leaves open translation of bovine lipogenic adaptations to cardiometabolic research.
Does nutritional status (underfeeding and refeeding) alter GLUT4 protein content and lipoprotein lipase activity in adipose tissues and muscles in adult cattle?
p-value: p=<0.05
Nutritional status induces species-specific metabolic adaptations in cattle, with divergent variations in GLUT4 protein content and LPL activity compared to rodents.
Bonnet et al. (2004) studied Nutritional status adaptation (n=13). Underfeeding and refeeding vs. Control diet (130% maintenance energy) was evaluated on GLUT4 protein content and lipoprotein lipase (LPL) activity (p=<0.05). Refeeding underfed adult cows increased GLUT4 protein content in perirenal adipose tissue by 250% and increased lipoprotein lipase activity across adipose and muscle tissues.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: