Key result
Flattening of temporal flow patterns measured by MR phase-contrast pulsatility correlated with the local severity of vascular occlusive disease.
Why the study?
Does phase-contrast MR flow measurement correlate with stenosis severity on digital subtraction angiography in patients with arteriosclerotic disease?
Observational (n=36)
Does phase-contrast MR flow measurement correlate with stenosis severity on digital subtraction angiography in patients with arteriosclerotic disease?
Phase-contrast MR flow measurements can quantify temporal flow patterns that correlate with the severity of vascular occlusive disease in iliofemoral arteries.
MR phase-contrast flow may noninvasively grade peripheral stenosis severity; leaves open prospective validation before clinical use.
Magnetic resonance (MR) flow measurements were obtained in six healthy volunteers and 30 patients with arteriosclerotic disease with a 1.5-T imager and a pulse sequence for flow quantification based on flow-induced phase shifts. The iliac arteries were investigated in eight and the femoral arteries in 28 subjects. A trigger pulse, followed by the acquisition of 30 evenly distributed data sets, was applied every second heartbeat, thus eliminating any acquisition gap in a full heart cycle. For quantitative analysis, flow velocity was plotted as a function of time. Systolic acceleration, postsystolic deceleration, and pulsatility of flow were calculated and compared with stenosis grades determined from recent intraarterial digital subtraction angiograms. The flattening of the temporal flow patterns correlated with local severity of vascular occlusive disease.
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Krug et al. (1995) conducted an observational in Arteriosclerotic disease (n=36). Magnetic resonance (MR) flow measurements vs. Intraarterial digital subtraction angiograms (reference standard) was evaluated on Correlation of flow velocity parameters (systolic acceleration, postsystolic deceleration, and pulsatility) with stenosis grades. Flattening of temporal flow patterns measured by MR phase-contrast pulsatility correlated with the local severity of vascular occlusive disease.
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