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August 1, 1997Journal of Biological ChemistryOpen Access

The Degradation of Apolipoprotein B100 Is Mediated by the Ubiquitin-proteasome Pathway and Involves Heat Shock Protein 70

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Authors

EFEdward A. FisherPreventive CardiologyMZMingyue ZhouDalian University of TechnologyDMDeborah M. MitchellHarvard University Press

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Fisher et al. (1997) studied this question.

synapsesocial.com/papers/6a6cf03d75498292b707ae6ahttps://doi.org/10.1074/jbc.272.33.20427
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Regulated intracellular degradation of apolipoprotein B in semipermeable HepG2 cells.1994 · 110 citations
  2. 2Degradation of a Mutant Secretory Protein, α1-Antitrypsin Z, in the Endoplasmic Reticulum Requires Proteasome Activity1996 · 369 citations
  3. 3Proteolysis and lipid-facilitated translocation are distinct but competitive processes that regulate secretion of apolipoprotein B in Hep G2 cells.1993 · 138 citations
  4. 4Apolipoprotein B Sequence Requirements for Hepatic Very Low Density Lipoprotein Assembly1996 · 71 citations
  5. 5The common variant of cystic fibrosis transmembrane conductance regulator is recognized by hsp70 and degraded in a pre-Golgi nonlysosomal compartment.1993 · 336 citations