Key result
This review summarizes older and recent findings on the pathways of apolipoprotein B degradation, focusing on events in the liver.
Design
Review
Authors
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May inform strategies targeting hepatic ApoB degradation to modulate atherogenic lipoproteins; leaves open clinical translation pending prospective validation.
ApoB degradation pathways in the liver play a central role in regulating the secretion of atherogenic lipoproteins.
Ginsberg et al. (2008) conducted a review in Apolipoprotein B metabolism. Pathways of apolipoprotein B degradation was evaluated. This review summarizes older and recent findings on the pathways of apolipoprotein B degradation, focusing on events in the liver.
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