February 27, 2008Clinical and Experimental Pharmacology and Physiology
Cardiovascular Risk Assessment Through Target Organ Damage: Role of Carotid to Femoral Pulse Wave Velocity
Key result
Aortic pulse wave velocity, an index of aortic stiffness, provides additional cardiovascular risk prediction beyond classical risk factors.
Why the study?
Does measuring aortic pulse wave velocity improve the prediction of cardiovascular-related death compared to classical risk factors alone?
Population
Patients undergoing cardiovascular risk assessment
Comparison
Aortic pulse wave velocity measurement vs Classical risk factor assessment alone
Design
Review
Authors
Discussion
Loading...
Member takes
Implication
Target-organ damage may refine individual CV risk prediction; leaves open guideline integration pending prospective validation.
Structured PICO
Does measuring aortic pulse wave velocity improve the prediction of cardiovascular-related death compared to classical risk factors alone?
P
Population
Patients undergoing cardiovascular risk assessment
E
Exposure
Aortic pulse wave velocity (aortic stiffness) measurement
C
Comparator
Classical risk factor assessment alone
O
Outcome
Prediction of cardiovascular-related death
Aortic pulse wave velocity is highlighted as a valuable tool for improving individual cardiovascular risk prediction beyond classical risk factors.
Limitations
- Lack of homogenization and spreading of the measurement technique
- Need for a reference value database
- Need for demonstration of added value in interventional trials
Cite This Study
Boutouyrie et al. (2008) conducted a review in Cardiovascular risk. Aortic pulse wave velocity (aortic stiffness) was evaluated on Cardiovascular-related death. Aortic pulse wave velocity, an index of aortic stiffness, provides additional cardiovascular risk prediction beyond classical risk factors.