Key result
C-reactive protein independently predicted all-cause mortality in patients with HFpEF (HR 1.20; 95% CI 1.02-1.40; P=0.018 per 1 SD increase).
Why the study?
Does C-reactive protein predict mortality in patients with HFpEF referred for coronary angiography?
Cohort (n=981)
Does C-reactive protein predict mortality in patients with HFpEF referred for coronary angiography?
Hazard Ratio: 1.2 (95% CI 1.02–1.4)
p-value: p=0.018
C-reactive protein is an independent and strong predictor of mortality in HFpEF, adding prognostic value to NT-proBNP.
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CRP may refine prognosis in HFpEF; leaves open whether it guides anti-inflammatory therapy.
Koller et al. (2014) conducted a cohort in Heart failure with preserved ejection fraction (HFpEF) (n=981). C-reactive protein (CRP) vs. Lower CRP levels was evaluated on All-cause mortality (HR 1.20, 95% CI 1.02-1.40, p=0.018). C-reactive protein independently predicted all-cause mortality in patients with HFpEF (HR 1.20; 95% CI 1.02-1.40; P=0.018 per 1 SD increase).
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