Key result
Progression through the 9-month school year was associated with a decrease in heart rate variability indicators of parasympathetic regulation and immune homeostasis among elderly teachers.
Why the study?
The preservation of health in educational participants requires diagnostic evaluation, prompting investigation into immune factors, cytokines, hormones, and autonomic heart rhythm regulation in elderly teachers across the school year.
Does the progression of the school year affect heart rate variability and immune homeostasis in elderly teachers?
Cohort (n=50)
Does the progression of the school year affect heart rate variability and immune homeostasis in elderly teachers?
The progression of the school year is associated with a decline in parasympathetic regulation and immune homeostasis in elderly teachers, highlighting the potential need for preventive health measures.
May indicate occupational stress effects on autonomic function in the elderly; hypothesis-generating and should not change practice.
The preservation of the health of participants in the educational process and the performance of comprehensive diagnostic measures with laboratory and instrumental methods occupy a significant place in a number of biomedical studies. The goal of the present work was to study the state of cellular factors of innate and adaptive immunity, IL-1β, 1α, IFN-γ cytokines, hormones, and autonomic regulation of the heart rhythm in elderly teachers in the school-year dynamics. The indices of spectral analysis of the heart rhythm (n = 50) at the beginning of the school year (background level) and after 5 and 9 months were studied. The state of cellular factors of innate and adaptive immunity was assessed via analysis of the functional activity of peripheral blood neutrophils by their ability to absorb latex particles, the oxygen-dependent metabolism, and the functional reserve. The lymphocyte-receptor landscape was assessed with flow cytofluorimetry, direct immunofluorescence, and solid-phase, enzyme-linked immunosorbent assay. The criteria of the Shapiro-Wilk test, the χ2 test, the one-sided Fisher exact test, and Student’s t-test were calculated. A decrease in heart rate variability indicators characterizing the activity of the parasympathetic regulation, as well as immune homeostasis among elderly teachers in the school-year dynamics, was found, which confirms the need to implement a set of preventive measures for health maintenance.
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Dolgova et al. (2020) conducted a cohort in Occupational stress in elderly teachers (n=50). School-year dynamics (occupational exposure over time) vs. Baseline (beginning of the school year) was evaluated on Heart rate variability indicators and immune homeostasis. Progression through the 9-month school year was associated with a decrease in heart rate variability indicators of parasympathetic regulation and immune homeostasis among elderly teachers.
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