Key result
Metabolically obese, normal-weight women had smaller LDL particles (P<0.01), higher oxidized LDL (P<0.05), and an unfavorable adipocytokine profile compared to pair-matched controls.
Why the study?
Do metabolically obese, normal-weight (MONW) women have a more atherogenic lipid and inflammatory profile compared to matched controls?
Population
50 non-obese Korean women aged 25-64 years with normal glucose tolerance, comprising 25 metabolically obese…
Design
Case-control
Authors
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May link visceral adiposity to CVD markers in MONW women; hypothesis-generating and leaves open prospective validation.
Case-Control (n=50)
Do metabolically obese, normal-weight (MONW) women have a more atherogenic lipid and inflammatory profile compared to matched controls?
Metabolically obese, normal-weight women exhibit an unfavorable inflammatory and atherogenic LDL profile despite lacking traditional CVD risk factors.
Hyun et al. (2008) conducted a case-control in Metabolically obese, normal-weight (n=50). Visceral fat adiposity ≥100 cm2 (MONW phenotype) vs. Visceral fat adiposity <100 cm2 was evaluated on Plasma lipid profiles and adipocytokines. Metabolically obese, normal-weight women had smaller LDL particles (P<0.01), higher oxidized LDL (P<0.05), and an unfavorable adipocytokine profile compared to pair-matched controls.
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