Key result
Patients with diabetes mellitus had a 3.111 times greater odds of developing coronary artery stenosis compared to those without diabetes.
Why the study?
Comorbid diseases are risk factors for atherosclerosis in CHD, and this study aimed to analyze the characteristics of coronary artery stenosis based on comorbidities in patients undergoing coronary angiography.
Does the presence of comorbidities (diabetes mellitus, hypertension, dyslipidemia) correlate with the severity and characteristics of coronary artery stenosis in patients with coronary heart disease undergoing coronary angiography?
Cross-Sectional (n=105)
No
Does the presence of comorbidities (diabetes mellitus, hypertension, dyslipidemia) correlate with the severity and characteristics of coronary artery stenosis in patients with coronary heart disease undergoing coronary angiography?
Odds Ratio: 3.111
p-value: p=0.007
In patients undergoing coronary angiography, diabetes mellitus is a strong independent predictor of more severe coronary artery stenosis, increasing the odds of significant stenosis by over 3-fold.
Comorbidity-linked stenosis patterns in CHD are hypothesis-generating; prospective studies needed before guiding angiography decisions.
Background: Comorbid diseases are a risk factor for atherosclerosis in coronary heart disease (CHD). Atherosclerosis causes the narrowing of the coronary arteries so that the heart muscles lack blood supply. Diagnostic coronary angiography is an invasive medical examination performed to determine the presence of coronary artery stenosis and to show the location and the number of coronary artery stenosis. Objective: This study aimed to analyze the characteristics of coronary artery stenosis based on comorbidities of patients with CHD undergoing coronary angiography. Methods: This analytical study was conducted using a cross-sectional design of 105 patients with CHD undergoing coronary angiographyat the catheterization laboratory at Bahteramas Hospital, Southeast Sulawesi, from January 1 to December 31, 2021.Statistical testing used Chi-squaretests with 95% confidence interval and significance set as p<0.05. Results: Most of the respondents were over 45 years old as many as 87 (82.9%), and most are male as many as 72 (68.6%). The category of the highest number of stenosis was less than two stenosis, namely 70 patients (66.7%) with the most common location as the Left Anterior Descending. The comorbidities category included a history of dyslipidemia in 41 people (39.0%), history of diabetes mellitus (DM) in 28 people (26.7%), and history of hypertension in 75 people (71.4%).The bivariate analysis showed a history of DM was associated with coronary artery stenosis (p-value = 0.007) with an Odds Ratio of 3.111. Conclusions: Patients with DM have 3.111 times greater possibility of developing stenosis of the coronary arteries.WC:246
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Haryati et al. (2023) conducted a cross-sectional in Coronary Heart Disease (n=105). Diabetes mellitus vs. No diabetes mellitus was evaluated on Coronary artery stenosis (OR 3.111, p=0.007). Patients with diabetes mellitus had a 3.111 times greater odds of developing coronary artery stenosis compared to those without diabetes.
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