Key result
Diabetes linked to nearly twofold higher left coronary artery stenosis rates vs non-diabetics.
Why the study?
The increasing global prevalence of diabetes mellitus necessitates a deeper understanding of its impact on coronary artery stenosis and clinical symptoms to guide early interventions and risk management.
Does diabetes mellitus increase the prevalence and severity of angiographic coronary artery stenosis in patients presenting with angina?
Population
170 diabetic and non-diabetic patients with angina in different age groups at Punjab Cardiology Lahore
Comparison
Diabetic patients vs non-diabetic patients
Design
Cross-sectional comparative study
Authors
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May inform age-specific risk stratification in diabetic angina patients; leaves open prospective validation of stenosis associations.
Cross-Sectional (n=170)
No
Does diabetes mellitus increase the prevalence and severity of angiographic coronary artery stenosis in patients presenting with angina?
Absolute Event Rate: 64.7% vs 35.3%
Diabetes mellitus is associated with a significantly higher prevalence and severity of multi-vessel coronary artery stenosis and severe clinical symptoms, particularly in middle-aged patients (40-60 years).
Tayyaba Ayoub (2025) conducted a cross-sectional in Coronary artery disease (n=170). Diabetes Mellitus vs. Non-diabetic patients was evaluated on Left coronary artery (LCA) stenosis. Diabetic patients exhibited significantly higher rates of left coronary artery stenosis compared to non-diabetics (64.7% vs. 35.3%), with the highest incidence observed in the 40–60 age group.
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