Key result
Sustained exposure to isocapnic hypoxia significantly reduced the stimulus interaction (Phi) between acute hypoxia and exercise as ventilatory stimuli (P < 0.02).
Why the study?
Does sustained hypoxia modify the interaction between hypoxia and exercise as ventilatory stimuli in humans?
Population
10 human subjects
Comparison
Sustained exposure to isocapnic hypoxia vs Exposure to air as a control
Design
Other
Authors
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Suggests altered ventilatory control after acclimatization; leaves open effects on altitude performance or hypoxic disease.
Does sustained hypoxia modify the interaction between hypoxia and exercise as ventilatory stimuli in humans?
p-value: p=<0.02
Sustained hypoxia attenuates the synergistic interaction between acute hypoxia and exercise on the peripheral chemoreflex in humans.
Wood et al. (2006) studied this question. Isocapnic hypoxia vs. Air was evaluated on Stimulus interaction between acute hypoxia and exercise (quantified by variable Phi) (p=<0.02). Sustained exposure to isocapnic hypoxia significantly reduced the stimulus interaction (Phi) between acute hypoxia and exercise as ventilatory stimuli (P < 0.02).
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