Key result
Moderate exercise increases the acute hypoxic ventilatory response by ~83% and abolishes resting decline.
Why the study?
The potential interactions between hypoxic ventilatory depression and exercise had not been studied.
Does moderate exercise modify the ventilatory response to sustained hypoxia in normal adult males?
Comparison
Isocapnic hypoxia during moderate exercise vs isocapnic hypoxia at rest
Design
Physiological study measuring ventilatory response
Follow-up
20 minutes
Authors
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May enhance hypoxic ventilatory stability during exercise in healthy adults; hypothesis-generating for clinical hypoxia or altitude applications.
Does moderate exercise modify the ventilatory response to sustained hypoxia in normal adult males?
Exercise potentiates the acute ventilatory response to hypoxia and abolishes the hypoxic decline seen at rest by increasing respiratory rate.
Ward et al. (1991) studied Healthy (n=7). Isocapnic hypoxia during moderate exercise vs. Isocapnic hypoxia at rest was evaluated on Ventilation (l/min). Moderate exercise potentiated the acute ventilatory response to hypoxia (increasing ventilation from 30.84 to 56.44 l/min) and abolished the hypoxic decline seen at rest.
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