Key result
Intravenous nitroglycerin infusion increased forearm arterial distensibility, though its overall effect on cardiac function is likely small as pulsatile work is only ~10% of total cardiac work.
Why the study?
Does intravenous nitroglycerin infusion increase forearm arterial distensibility?
Population
Human subjects (implied by 'subject's forearm')
Comparison
Intravenous nitroglycerin infusion vs Baseline measurements before infusion, with…
Design
Other
Authors
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Nitroglycerin may reduce LV workload partly via enhanced arterial distensibility; leaves open its relative contribution versus SVR reduction in current vasodilator use.
Does intravenous nitroglycerin infusion increase forearm arterial distensibility?
Nitroglycerin increases arterial distensibility independent of blood pressure changes, providing another mechanism for reducing left ventricular afterload.
Smulyan et al. (1986) studied this question. Intravenous nitroglycerin vs. Before infusion (baseline) was evaluated on Volume distensibility of forearm arteries. Intravenous nitroglycerin infusion increased forearm arterial distensibility, though its overall effect on cardiac function is likely small as pulsatile work is only ~10% of total cardiac work.
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