Why the study?
Does intravenous nitroglycerin improve peripheral large artery compliance and diameter in patients with sustained essential hypertension?
Population
11 patients with sustained essential hypertension
Comparison
Intravenous administration of nitroglycerin vs Baseline (before administration)
Design
Cohort
Follow-up
15 minutes
Authors
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Acute nitroglycerin effects on compliance remain hypothesis-generating in hypertension; leaves open outcome impact pending randomized trials.
Does intravenous nitroglycerin improve peripheral large artery compliance and diameter in patients with sustained essential hypertension?
Intravenous nitroglycerin directly increases peripheral large artery diameter and compliance in hypertensive patients, leading to a predominant decrease in systolic pressure.
Simon et al. (1982) studied this question.
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