Key result
Both decreased (lowest quartile, HR 1.8; 95% CI 1.0-3.2) and increased (highest quartile, HR 2.3; 95% CI 1.3-4.0) heart rate variability predicted cardiac mortality in older adults.
Why the study?
Does heart rate variability on a 10-second ECG predict cardiac mortality in elderly individuals?
Population
5,272 men and women aged >=55 years from a population-based cohort, excluding subjects with arrhythmia and…
Comparison
Heart rate variability measured on a standard… vs Third quartile of SDNN
Design
Cohort
Follow-up
mean 4 years
Authors
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May inform ECG-based mortality risk assessment in older adults; leaves open prospective validation before clinical adoption.
Cohort (n=5,272)
Does heart rate variability on a 10-second ECG predict cardiac mortality in elderly individuals?
Hazard Ratio: 1.8 (95% CI 1–3.2)
Both decreased and increased heart rate variability on a standard 10-second ECG are associated with an increased risk of cardiac mortality in the elderly.
Bruyne et al. (1999) conducted a cohort in General elderly population (n=5,272). Decreased and increased heart rate variability (SDNN) vs. Third quartile of SDNN was evaluated on Cardiac mortality (HR 1.8, 95% CI 1.0-3.2). Both decreased (lowest quartile, HR 1.8; 95% CI 1.0-3.2) and increased (highest quartile, HR 2.3; 95% CI 1.3-4.0) heart rate variability predicted cardiac mortality in older adults.
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