Key result
The high-sensitivity cardiac Troponin T assay significantly increased the detection of elevated troponin levels compared to the standard assay (76% vs 35%, p<0.001) in geriatric patients.
Why the study?
Does the high sensitivity cardiac Troponin T (cTnThs) assay improve early detection of NSTEMI compared to the fourth-generation cTnT assay in geriatric patients?
Population
253 geriatric patients with suspected NSTEMI admitted to a Department of Geriatric Medicine, mean age 82 ± 8…
Comparison
High sensitivity cardiac Troponin T (cTnThs) assay vs Fourth-generation cardiac troponin T (cTnT) assay
Design
Cohort
Authors
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May support hs-cTnT adoption in geriatric NSTE-MI; leaves open need for prospective validation before practice change.
Observational (n=253)
No
Does the high sensitivity cardiac Troponin T (cTnThs) assay improve early detection of NSTEMI compared to the fourth-generation cTnT assay in geriatric patients?
Absolute Event Rate: 76% vs 35%
p-value: p=<0.001
The high-sensitivity troponin T assay allows for earlier diagnosis of NSTEMI in geriatric patients but significantly increases the detection of elevated troponin without a coronary cause.
Bahrmann et al. (2012) conducted an observational in Suspected NSTEMI (n=253). High sensitivity cardiac Troponin T (cTnThs) assay vs. Fourth-generation cardiac troponin T (cTnT) assay was evaluated on Proportion of patients with elevated cardiac troponin levels (p=<0.001). The high-sensitivity cardiac Troponin T assay significantly increased the detection of elevated troponin levels compared to the standard assay (76% vs 35%, p<0.001) in geriatric patients.
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