Key result
Recent antecedent hypoglycemia did not increase blood-to-brain glucose transport compared to euglycemia (22.4 vs 24.6 micromol/100g/min) in healthy young adults.
Why the study?
Does recent antecedent hypoglycemia increase blood-to-brain glucose transport during subsequent hypoglycemia in healthy young adults?
Population
17 healthy young adults
Comparison
Approximately 24 h of interprandial hypoglycemia vs Euglycemia
Design
Other
Authors
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Shifts thresholds in healthy adults; leaves open extension to hypoglycemia unawareness management in type 1 diabetes.
Does recent antecedent hypoglycemia increase blood-to-brain glucose transport during subsequent hypoglycemia in healthy young adults?
Absolute Event Rate: 22.4% vs 24.6%
Recent antecedent hypoglycemia does not increase global blood-to-brain glucose transport, cerebral glucose metabolism, or cerebral blood flow during subsequent hypoglycemia in healthy young adults.
Segel et al. (2001) studied Healthy (n=17). Recent antecedent hypoglycemia vs. Euglycemia was evaluated on Rates of blood-to-brain glucose transport (micromol/100g/min). Recent antecedent hypoglycemia did not increase blood-to-brain glucose transport compared to euglycemia (22.4 vs 24.6 micromol/100g/min) in healthy young adults.
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