Key result
Non-nephrotic uremia was associated with increased basal plasma triglycerides (164 mg/100 ml in non-dialysis, 276 mg/100 ml in dialysis), which correlated with insulin levels (r=0.58, P<0.02).
Population
Patients with non-nephrotic uremia and nonuremic control subjects of the same weight.
Design
Cross-sectional
Authors
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May link hyperinsulinemia to TG elevation in uremia; hypothesis-generating and requires prospective confirmation before clinical consideration.
Observational (n=38)
Hypertriglyceridemia is a consequence of non-nephrotic uremia, likely due to both increased triglyceride production and decreased removal capacity.
John D. Bagdade (1970) conducted an observational in Non-nephrotic uremia (n=38). Non-nephrotic uremia vs. Nonuremic subjects was evaluated on Basal plasma triglyceride (TG) concentrations. Non-nephrotic uremia was associated with increased basal plasma triglycerides (164 mg/100 ml in non-dialysis, 276 mg/100 ml in dialysis), which correlated with insulin levels (r=0.58, P<0.02).
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