Key result
Non-nephrotic uremia was associated with elevated basal plasma triglycerides in patients not on dialysis (164 ± 62 mg/100 ml) and those on dialysis (276 ± 250 mg/100 ml).
Population
38 patients with uremia and nonuremic control subjects of the same weight.
Design
Cross-sectional
Authors
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May link insulin resistance to TG elevation in dialysis patients; leaves open causal role in uremic dyslipidemia.
Observational (n=38)
Hypertriglyceridemia is a previously unrecognized consequence of non-nephrotic uremia, likely driven by both increased hepatic synthesis linked to hyperinsulinemia and decreased triglyceride assimilation.
John D. Bagdade (1970) conducted an observational in Non-nephrotic uremia (n=38). Non-nephrotic uremia vs. Nonuremic subjects was evaluated on Basal plasma triglyceride concentrations. Non-nephrotic uremia was associated with elevated basal plasma triglycerides in patients not on dialysis (164 ± 62 mg/100 ml) and those on dialysis (276 ± 250 mg/100 ml).
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