Key result
Cancer cachexia was associated with significantly lower heart weight compared to non-cachectic cancer subjects (363.1 vs. 447.0 g, P<0.001) and cancer-free controls (P<0.05).
Why the study?
Is cancer cachexia associated with decreased heart weight and cardiac muscle wasting in patients with cancer?
Observational (n=219)
Is cancer cachexia associated with decreased heart weight and cardiac muscle wasting in patients with cancer?
Absolute Event Rate: 363.1% vs 447%
p-value: p=< 0.001
Cancer cachexia is associated with significant cardiac muscle wasting, highlighting the potential importance of screening for cardiac involvement in cachectic cancer patients.
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Suggests cardiac wasting in terminal cancer; hypothesis-generating and should not yet change practice.
Barkhudaryan et al. (2017) conducted an observational in Cancer cachexia (n=219). Cancer cachexia vs. Non-cachectic cancer subjects and cancer-free controls was evaluated on Heart weight (p=< 0.001). Cancer cachexia was associated with significantly lower heart weight compared to non-cachectic cancer subjects (363.1 vs. 447.0 g, P<0.001) and cancer-free controls (P<0.05).
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