Key result
Sugammadex was associated with a lower incidence of post-operative pleural effusion compared to neostigmine in patients undergoing laparoscopic gastrectomy (18% vs. 23.4%, p=0.02).
Why the study?
Sugammadex reduces post-operative residual neuromuscular blockade, but its effect on post-operative pulmonary complications remains unclear.
Does sugammadex reduce post-operative pulmonary complications in patients undergoing laparoscopic gastrectomy compared to neostigmine?
Population
1232 matched patients undergoing laparoscopic gastrectomy between 2013 and 2017
Comparison
Sugammadex vs neostigmine
Design
Retrospective propensity score-matched cohort study
Authors
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May inform reversal choice in laparoscopic gastrectomy; leaves open randomized confirmation of reduced pulmonary complications.
Cohort (n=1,232)
Does sugammadex reduce post-operative pulmonary complications in patients undergoing laparoscopic gastrectomy compared to neostigmine?
Absolute Event Rate: 18% vs 23.4%
p-value: p=0.02
Sugammadex is associated with a lower incidence of post-operative pleural effusion compared to neostigmine in patients undergoing laparoscopic gastrectomy.
Han et al. (2020) conducted a cohort in Laparoscopic gastrectomy (n=1,232). Sugammadex vs. Neostigmine was evaluated on Post-operative pleural effusion (p=0.02). Sugammadex was associated with a lower incidence of post-operative pleural effusion compared to neostigmine in patients undergoing laparoscopic gastrectomy (18% vs. 23.4%, p=0.02).
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