Key result
In over 4000 twin pairs, heritability estimates were 52-66% for systolic blood pressure and 44-66% for diastolic blood pressure, with no evidence of sex differences.
Population
Over 4000 twin pairs from six different European countries and Australia
Design
Review
Authors
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Highlights genetic influences on BP across sexes; leaves open specific loci and interactions for genomic research.
Effect estimate: 52-66% for SBP, 44-66% for DBP
Twin studies demonstrate a strong genetic component to blood pressure, with heritability estimates of 52-66% for systolic and 44-66% for diastolic blood pressure.
Evans et al. (2003) conducted a review in Coronary heart disease and blood pressure (n=8,000). Genetic factors (heritability) vs. Shared family environment was evaluated on Heritability of systolic and diastolic blood pressure (52-66% for SBP, 44-66% for DBP). In over 4000 twin pairs, heritability estimates were 52-66% for systolic blood pressure and 44-66% for diastolic blood pressure, with no evidence of sex differences.
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