Key result
Genetic factors account for approximately 54% of the variance in systolic blood pressure and 49% in diastolic blood pressure, with estimates being higher when using an AE rather than an ACE model.
Population
10,613 independent twins from 17 studies
Design
Meta-analysis
Authors
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May inform familial hypertension risk assessment; confirms twin meta-analyses while leaving AE model inflation open.
Systematic Review (n=10,613)
Effect estimate: Heritability 0.54 (95% CI 0.48-0.60)
Heritability estimates for both SBP and DBP are approximately 50% in twin studies, though estimates may be inflated when using an AE model compared to an ACE model.
Wang et al. (2015) conducted a systematic review in Blood pressure and heart rate variance (n=10,613). Genetic factors (heritability) was evaluated on Weighted mean heritability of systolic blood pressure (SBP) (Heritability 0.54, 95% CI 0.48-0.60). Genetic factors account for approximately 54% of the variance in systolic blood pressure and 49% in diastolic blood pressure, with estimates being higher when using an AE rather than an ACE model.
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