Key result
Body fat percentage was non-linearly correlated with the Cardio-Ankle Vascular Index, demonstrating a significant positive association when body fat percentage was ≥20.6%.
Why the study?
The study was conducted to evaluate arteriosclerosis using the Cardio-Ankle Vascular Index and explore the relationship between body fat percentage and CAVI.
Does body fat percentage correlate with arteriosclerosis assessed by Cardio-Ankle Vascular Index in Chinese patients?
Cross-Sectional (n=1,152)
No
Does body fat percentage correlate with arteriosclerosis assessed by Cardio-Ankle Vascular Index in Chinese patients?
Body fat percentage demonstrates a non-linear association with arterial stiffness, where risk increases significantly above a threshold body fat percentage of 20.6%.
Should not yet change vascular risk stratification; leaves open whether body fat reduction improves arterial stiffness markers.
OBJECTIVE: To evaluate arteriosclerosis using Cardio-Ankle Vascular Index (CAVI) and to explore the relation between the body fat percentage (BFP) and CAVI. DESIGN: A retrospective observational study. SETTING AND PARTICIPANTS: A total of 1152 patients admitted to a geriatric unit and general practice at a mega hospital in Wuhan, China, from November 2018 to November 2019 were included in this study. PRIMARY OUTCOME: Association between BFP and CAVI. RESULTS: Multiple linear regression analysis showed that BFP was positively correlated with CAVI after correction for potential confounding variables (β=0.03; 95% CI: 0.01 to 0.05); this association persisted after BFP was treated by quartile categorical variables and the trend test was statistically significant (p for trend=0.002). Meanwhile, the generalised additive model showed a non-linear association between BFP and CAVI. When BFP<20.6%, BFP is not associated with CAVI for (β=-0.02; 95% CI: -0.06 to 0.03), but when BFP≥20.6%, there is a linear positive association between BFP and CAVI (β=0.05; 95% CI: 0.02 to 0.07). Subgroup analysis showed that there was an interaction between BFP and CAVI in the age stratification (p interaction=0.038). CONCLUSION: BFP was non-linearly correlated with CAVI, with a 0.05 increase in CAVI for every 1% increase in BFP when BFP≥20.6% and a 0.03 increase in CAVI in those >65 years of age.
No takes yet. Share an insight, caveat, or question.
He et al. (2022) reported a cross-sectional. Body fat percentage was evaluated on Association between body fat percentage and Cardio-Ankle Vascular Index (β=0.03, 95% CI 0.01 to 0.05, p=0.013). Body fat percentage was non-linearly correlated with the Cardio-Ankle Vascular Index, demonstrating a significant positive association when body fat percentage was ≥20.6%.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: