Key result
An integrated evaluation of blood pressure, plasma volume, extracellular fluid volume, and plasma renin concentration allows separation between essential and renovascular hypertension.
Why the study?
Does plasma renin concentration, alone or in combination with plasma and extracellular fluid volume, differentiate renovascular from essential hypertension and predict blood pressure response to surgery?
Population
212 hypertensive patients, including a subset of 14 patients with essential hypertension and 17 patients…
Comparison
Measurement of plasma renin concentration… vs Essential hypertension vs. renovascular…
Design
Cohort
Follow-up
12 months or longer (for surgical patients)
Authors
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PRC assessment in hypertension remains hypothesis-generating; prospective studies needed to define diagnostic value.
Observational (n=212)
Does plasma renin concentration, alone or in combination with plasma and extracellular fluid volume, differentiate renovascular from essential hypertension and predict blood pressure response to surgery?
Bianchi et al. (1970) conducted an observational in Hypertension (n=212). Plasma renin concentration, plasma volume, and extracellular fluid volume vs. Essential hypertension or normal subjects was evaluated on Blood pressure reduction after surgery for unilateral renal disease. An integrated evaluation of blood pressure, plasma volume, extracellular fluid volume, and plasma renin concentration allows separation between essential and renovascular hypertension.