Key result
Renal revascularization significantly decreased blood urea nitrogen and serum creatinine in 13 azotemic patients, but did not significantly affect normal glomerular filtration rate in 20 patients.
Why the study?
Does renal revascularization improve kidney function in patients with renal arterial hypertension?
Population
53 patients with renal arterial hypertension
Comparison
Renal revascularization vs Preoperative functional status
Design
Cohort
Authors
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May support selective use in azotemia; leaves open benefit for normal GFR and requires randomized confirmation.
Observational (n=53)
Does renal revascularization improve kidney function in patients with renal arterial hypertension?
Renal revascularization in patients with renal arterial hypertension improves kidney function primarily in those with preoperative azotemia, while inducing excessive natriuresis and diuresis in the revascularized kidney.
Simon et al. (1964) conducted an observational in Renal arterial hypertension (n=53). Renal revascularization vs. Preoperative status was evaluated on Kidney function (blood urea nitrogen, serum creatinine, glomerular filtration rate, renal blood flow). Renal revascularization significantly decreased blood urea nitrogen and serum creatinine in 13 azotemic patients, but did not significantly affect normal glomerular filtration rate in 20 patients.
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