August 1, 2026Journal of the American College of CardiologyOpen Access

Ventricular Arrhythmia After Cardiac Surgery

Q: What are the key findings of this study?

Post-operative ventricular arrhythmia after cardiac surgery was associated with substantially increased adjusted long-term mortality over 3.5 years of follow-up (HR 2.53; P<0.001).

Q: What is the clinical evidence from this study?

Study design: Cohort. Population: Cardiac surgery (n=14720). Intervention: Post-operative ventricular arrhythmia (POVA) vs. No post-operative ventricular arrhythmia. Primary outcome: Long-term all-cause mortality (HR 2.53, p=<0.001).

Q: What question did this study set out to answer?

The aim is to investigate the prevalence, predictors, and outcomes of post-operative ventricular arrhythmia after cardiac surgery.

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Key result

Post-operative ventricular arrhythmia is linked to ~153% higher long-term mortality after cardiac surgery.

HR 2.53
P<0.001
n=14,720

Why the study?

New-onset post-operative ventricular arrhythmia after cardiac surgery is uncommon and has controversial prognostic value.

Population

14,720 consecutive patients undergoing cardiac surgery at Emory University

Comparison

Patients with post-operative ventricular arrhythmia vs without post-operative ventricular arrhythmia

Design

Cohort study

Follow-up

3.5 years

Authors

MEMikhael F. El‐Chami FSFadi Sawaya PKPatrick Kilgo

Discussion

Member takes

Overview

Randomized trial investigates predictors and outcomes of post-operative ventricular arrhythmia, indicating risk factors for long-term mortality.

Key Points

The aim is to investigate the prevalence, predictors, and outcomes of post-operative ventricular arrhythmia after cardiac surgery.
Included 14,720 patients undergoing cardiac surgery between January 2004 and July 2010.
Constructed multivariable regression models to identify risk factors for post-operative ventricular arrhythmia.
Assessed all-cause mortality using Social Security Administration death records.
Post-operative ventricular arrhythmia occurred in 248 patients (1.7%).
Older age (OR: 1.018, p < 0.001) and emergent surgery (OR: 1.77, p = 0.019) increased POVA risk.
POVA was linked to a hazard rate of 2.53 for long-term mortality (p < 0.001) over 3.5 years.

Study Design

Type

Cohort (n=14,720)

Multicenter

PICO

Population

14,720 consecutive patients undergoing cardiac surgery, followed for 3.5 years to assess the impact of post-operative ventricular arrhythmia on long-term survival.

Exposure / Comparator

Post-operative ventricular arrhythmia (POVA) vs No post-operative ventricular arrhythmia

Primary Outcome

Long-term all-cause mortality — HR 2.53, p=<0.001

Main Result

Hazard Ratio: 2.53

p-value: p=<0.001

Cite This Study

El‐Chami et al. (2012) conducted a cohort in Cardiac surgery (n=14,720). Post-operative ventricular arrhythmia (POVA) vs. No post-operative ventricular arrhythmia was evaluated on Long-term all-cause mortality (HR 2.53, p=<0.001). Post-operative ventricular arrhythmia after cardiac surgery was associated with substantially increased adjusted long-term mortality over 3.5 years of follow-up (HR 2.53; P<0.001).

synapsesocial.com/papers/6a6e62bf09fb4e44f899ddc7 https://doi.org/10.1016/j.jacc.2012.08.1011

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August 1, 2026Journal of the American College of CardiologyOpen Access

Ventricular Arrhythmia After Cardiac Surgery

View Full Paper

Ask AI

Bookmark

Key result

Post-operative ventricular arrhythmia is linked to ~153% higher long-term mortality after cardiac surgery.

HR 2.53
P<0.001
n=14,720

Why the study?

New-onset post-operative ventricular arrhythmia after cardiac surgery is uncommon and has controversial prognostic value.

Population

14,720 consecutive patients undergoing cardiac surgery at Emory University

Comparison

Patients with post-operative ventricular arrhythmia vs without post-operative ventricular arrhythmia

Design

Cohort study

Follow-up

3.5 years

Authors

MEMikhael F. El‐Chami FSFadi Sawaya PKPatrick Kilgo

Discussion

Member takes

Overview

Randomized trial investigates predictors and outcomes of post-operative ventricular arrhythmia, indicating risk factors for long-term mortality.

Key Points

The aim is to investigate the prevalence, predictors, and outcomes of post-operative ventricular arrhythmia after cardiac surgery.
Included 14,720 patients undergoing cardiac surgery between January 2004 and July 2010.
Constructed multivariable regression models to identify risk factors for post-operative ventricular arrhythmia.
Assessed all-cause mortality using Social Security Administration death records.
Post-operative ventricular arrhythmia occurred in 248 patients (1.7%).
Older age (OR: 1.018, p < 0.001) and emergent surgery (OR: 1.77, p = 0.019) increased POVA risk.
POVA was linked to a hazard rate of 2.53 for long-term mortality (p < 0.001) over 3.5 years.

Study Design

Type

Cohort (n=14,720)

Multicenter

PICO

Population

14,720 consecutive patients undergoing cardiac surgery, followed for 3.5 years to assess the impact of post-operative ventricular arrhythmia on long-term survival.

Exposure / Comparator

Post-operative ventricular arrhythmia (POVA) vs No post-operative ventricular arrhythmia

Primary Outcome

Long-term all-cause mortality — HR 2.53, p=<0.001

Main Result

Hazard Ratio: 2.53

p-value: p=<0.001

Cite This Study

synapsesocial.com/papers/6a6e62bf09fb4e44f899ddc7 https://doi.org/10.1016/j.jacc.2012.08.1011

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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