Key result
The complete 7212-nucleotide sequence of the human rhinovirus type 14 RNA genome was determined, revealing a single large open reading frame and 44-65% homology with poliovirus.
Population
Human rhinovirus type 14 genomic RNA cloned in Escherichia coli
Design
Preclinical
Authors
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Enables molecular studies of rhinovirus; leaves open targeted antiviral development leveraging picornavirus homology.
The complete nucleotide sequence of human rhinovirus type 14 was determined, revealing significant homology with poliovirus and mapping structural and non-structural proteins.
Callahan et al. (1985) studied Human rhinovirus type 14. The complete 7212-nucleotide sequence of the human rhinovirus type 14 RNA genome was determined, revealing a single large open reading frame and 44-65% homology with poliovirus.
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