Key result
Pulmonary artery hypertension was associated with coronary sinus dilation on chest CT (9.4 mm vs 7.05 mm in controls), which correlated with mean pulmonary artery pressure (r=0.568, P=0.005).
Why the study?
Does coronary sinus diameter measured on chest CT correlate with pulmonary artery pressures in patients with pulmonary artery hypertension?
Cross-Sectional (n=84)
Does coronary sinus diameter measured on chest CT correlate with pulmonary artery pressures in patients with pulmonary artery hypertension?
Absolute Event Rate: 9.4% vs 7.05%
The coronary sinus can be routinely measured on chest CT, and its dilation serves as a non-invasive indicator of increased pulmonary artery pressures in patients with PAH.
Routine chest CT identifies the CS in all patients; leaves open its diagnostic value in PAH pending prospective validation.
OBJECTIVE: To identify and measure the coronary sinus (CS) in patients with and without pulmonary artery hypertension (PAH) using chest computed tomography (CT). METHODS: Using a 4-channel GE LightSpeed CT scanner, nongated axial chest CT images were obtained after intravenous injection of contrast material. Catheterization of the right side of the heart was performed in patients with known or suspected PAH. RESULTS: The CS was identified in all 60 patients (mean +/- SD, 60.5 +/- 17.5 years; 45% men) without PAH (control group) (mean +/- SD, diameter 7.05 +/- 1.90 mm). In 24 patients (9 men; average age +/- SD, 54.1 +/- 14.5 years) with known or suspected PAH (study group), pulmonary artery (PA) pressures were increased; the CS was dilated (mean +/- SD, 9.4 +/- 4. 2 mm); and its size correlated with right atrial pressure (r = 0.358, P = 0.061), mean PA pressure (r = 0.568, P = 0.005), systolic PA pressure (r = 0.375, P = 0.071), and diastolic PA (r = 0.561, P = 0.004). CONCLUSION: The CS is routinely visualized and measurable on chest CT. In patients with PAH, CS dilation is associated with increased PA pressures.
No takes yet. Share an insight, caveat, or question.
Isaacs et al. (2009) conducted a cross-sectional in Pulmonary artery hypertension (n=84). Pulmonary artery hypertension vs. Patients without pulmonary artery hypertension was evaluated on Coronary sinus diameter. Pulmonary artery hypertension was associated with coronary sinus dilation on chest CT (9.4 mm vs 7.05 mm in controls), which correlated with mean pulmonary artery pressure (r=0.568, P=0.005).